PJB-2011-32
BIOLOGICAL SCREENING OF ZIZYPHUS OXYPHYLLA EDGEW STEM
MUHAMMAD NISAR1*, WAQAR AHMAD KALEEM2, MUGHAL QAYUM2, INAMULLAH KHAN MARWAT2, M. ZIA-UL-HAQ4, IHSAN ALI1 AND M. I. CHOUDHARY3
Abstract
Crude methanolic extract and various fractions of Zizyphus oxyphylla Edgew stem were screened for antibacterial, antifungal, phytotoxic, cytotoxic and insecticidal activities. Antibacterial bioassay performed against six bacteria viz., Escherichia coli, Bacillus subtilis, Shigella flexenari, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella typhi indicated that neither crude extract nor any of subsequent fraction exhibited antibacterial potential. The antifungal activity of the extract and fractions screened against five fungal strains viz., Candida albicans, Aspergilus flavus, Microsporum canis, Fusarium solani and Candida glaberata indicated non significant results. Similarly neither of the crude or subsequent fractions showed any cytotoxicty or insecticidal activity. However crude extract and fractions showed significant phytotoxicity at higher doses.
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