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Abstract

Pakistan is rich in medicinal plant resources and harnessing these local pharmaceutical resources can help reduce the country’s reliance on imported plant-based medications, leading to significant cost savings. This review provides timely insights into how plant based compounds contribute to the diabetes management. Beyond therapeutic potential the phytocompound holds economic value and minimum side effects. However, the literature is scanty regarding the potential of Pakistan’s indigenous medicinal plants for diabetes management across different geographic regions. This review summarizes the scattered data on native antidiabetic plants, highlighting their bioactive compounds and pharmacological properties to support future research and development in this area. It specifically examines key medicinal plants, including Bitter Apple/Burambba (Citrullus colocynthis), Paneer (Withania coagulans), Kunwar Boti (Aloe barbadensis), Neem (Azadirachta indica), Jamun (Syzygium cumini), Ginger (Zingiber officinale), Turmeric (Curcuma longa), Moringa (Moringa oleifera), Amla (Phyllanthus emblica), Fenugreek (Trigonella foenum-graecum), Cinnamon (Cinnamomum zeylanicum), Bitter Melon (Momordica charantia), Green Tea (Camellia sinensis), and Garlic (Allium sativum). This study provides comprehensive understanding of antidiabetic properties of different plant parts, including roots, stems, leaves, flowers, and fruits/seeds, and assessing their flavonoid, alkaloid, saponin, tannin, steroid, glycoside, and carbohydrate content. Serving as a foundational reference for future pharmacological and clinical research and offers novel insights into the integration of indigenous medicinal flora with evidence based diabetes management strategies.

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