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Studies on the biological activity of different populations of the medicinal plant Rhodiola rosea L. (golden root)

Moldir Zhumagul, Meryuert Kurmanbayeva, Serik Kubentayev, Alfiya Kurmantayeva, Aknur Turgumbayeva, Indira Nurpeissova, Natalya Cherepkova and Aizhan Moldakaryzova

Rhodiola rosea  species have a wide spectrum of therapeutic action and are actively used as a tonic, adaptogenic, antidepressant, anti-inflammatory, and for other treatments. We analyzed the phytochemical composition of essential oils of R. rosea from the high mountainous regions of Kazakhstan Altai (Eastern Kazakhstan) and Austria. The results showed high percentages of cinnamyl alcohol (31.28%), Cyclobutanecarboxylic acid, 3-methylbutyl ester (9.65%) (9.65%) in the roots of R. rosea. of Kazakhstan Altai and the content of cinnamyl alcohol (27.28%), Tyrosol in the root (19.39%) native to Hochkar, Austrian Alps. The antioxidant activity and cytotoxicity of species of different populations of R. rosea were also studied. The results revealed antioxidant activity of this species. Biologically active compounds of R. rosea have many pharmaceutical effects in various diseases. The formula of essential oils from the root of R. rosea were analyzed using GC-MS. The antioxidative activity was determined by FRAP method. The essential oil has shown a low antioxidative activity compared to butylhydroxyanisole(BHA)at concentrations of 0.25-1.0 mg ml-1, which confirms the antioxidative properties of this species. The results of cytotoxic activity against the larvae of Artemia salina has revealed that its essential oil shows lethal toxicity at all tested concentrations, proving the cytoxicity of golden root.  

To Cite this article: Zhumagul, M., M. Kurmanbayeva, S. Kubentayev, A. Kurmantayeva, A. Turgumbayeva, I. Nurpeissova, N. Cherepkova and A. Moldakaryzova. 2023. Studies on the biological activity of different populations of the medicinal plant Rhodiola rosea L. (golden root). Pak. J. Bot., 55(5): DOI:  

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