PJB-2019-708
PLANT BASED MICROEMULSIONS: AN IDEAL DRUG CARRIER SYSTEM FOR IMPROVED THERAPY
Ayesha Akram
Abstract
The current review presents plant based microemulsions as most promising and novel system for improving stability, bioavailability and delivery. Microemulsions are thermodynamically stable, optically isotropic and low viscosity systems which are formed spontaneously without large energy input. They can be used as delivery system for various types of drugs and plant extracts because of their large surface area and very small particle size. They reduce the drug toxicity, increase their bioavailability and stability. The type of microemulsion formed and their phases can be determined through phase diagram studies. They can be used for the delivery of hydrophilic as well as hydrophobic drugs and plant extracts. Recently, the use of plant extracts for therapeutic purposes hold great attention because of their less adverse reactions and human nature of using natural compounds for cure of disease. This review presents an overview of microemulsion formulation basics, its differences from other emulsion systems and preparation of microemulsions based on different plant extracts along with their therapeutic purposes.
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