PJB-2018-1031
Chemical composition and antibacterial activity of Anisotes trisulcus
Rafiq Lone
Abstract
Nowadays medicinal plants have a great stature as they are considered the main resources of medicinal drugs. In the present study, we investigated the antibacterial activity of Anisotes trisulcus (Forssk.) Nees (Acanthaceae) against various bacterial species namely Staphylococcus aureus, Pseudomonas aureus, Escherichia coli, Shigella sonnei, Bacillus subtillis. Leaves and stems of these plants were separately extracted using five different solvents (ethanol, chloroform, petroleum ether, ethyl acetate and n-butanol). Each extract was studied on the five studied bacterial strains to calculate the minimum inhibitory concentration (MIC). The obtained results showed that the stem extract using ethyl acetate had the lowest MIC for Staphylococcus aureus with 0.05 mg/ml, followed by 0.12 mg/ml for the petroleum ether extract on the same species. The chemical composition analysis of the stem extract using ethyl acetate solvent showed several important chemical compounds including preganine, 7-hydroxy vasicine, 5-methoxypeganin, pentadecanal and undecanoic acid. This study could be considered as the bedrock for further studied to examine the medicinal potential of A. trisulcus plants.
To Cite this article:
Download
