PJB-2024-282
JUMANAH ALI AL-FARRAJ
Abstract
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Salicylic acid, a plant hormone that belongs to the phenolic group, serves various purposes. Several studies have been done on it because it helps plants become more resilient to biotic and abiotic stresses. Salicylic acid is also used to make medicines that lower body temperature, relieve pain, and treat various skin conditions. Salicylic acid is also applied topically to treat acne, cure warts, and treat other skin disorders. Furthermore, it is employed as a food and certain cosmetic preservatives. The study you described involving the use of different concentrations of salicylic acid in the Allium test provides valuable insights into its cytotoxic effects and its impact on the mitotic index (MI) and chromosomal abnormalities for 12 and 24 hours. Based on the results, it appears that higher concentrations of salicylic acid and longer exposure durations led to a decrease in the mitotic index. Additionally, the study found an increase in the rate of chromosomal abnormalities at higher concentrations and longer exposure durations of salicylic acid. Overall, these findings indicate that salicylic acid can exert cytotoxic and genotoxic effects on Allium cells, with the severity of these effects depending on the concentration and duration of exposure. These results contribute to our understanding of the potential risks associated with exposure to salicylic acid and highlight the importance of assessing its safety profile in various biological systems.
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