Paper Details

PJB-2024-168

Research trends and hotspots of traditional chinese medicinal plant rhubarb:a bibliometric analysis and visualization

WANG LINGLING
Abstract


Rhubarb is a plant that contains numerous chemical substances and has been found to have a significant curative effect, particularly in the treatment of constipation. The purpose of this study is to utilize bibliometrics based on Web of Science in order to explore the research trends and hotspots related to rhubarb. The research focused on rhubarb and utilized a significant number of literature sources published between 2000 and 2021. To comprehensively review these sources, the study employed CiteSpace, VOSviewer, and R language to examine various aspects, including research fields, publishing institutions, journals, and authors. The study found that a total of 1552 articles were retrieved, indicating a steady increase in the number of published papers. Notably, the largest increase occurred between 2010 and 2021. The research frontiers encompass a range of disciplines, including Pharmacology Pharmacy, Chemistry, Biochemistry Molecular Biology, and Integrative Complementary Medicine. The research fields mentioned above have China at their core, with the Chinese Academy of Sciences making the greatest contribution through the publication of 91 papers. Network analysis of keywords revealed that rhubarb, emodin, and anthraquinones were the most prominent. Co-citation analysis further highlighted that anthraquinones, pharmacokinetics, and emodin were the main research hotspots. Research on rhubarb has taken a diversified perspective, resulting in significant progress in identifying active substances and understanding pharmacological activities. However, the quality control system and resource development and utilization of rhubarb are relatively weak. As a result, research on the metabolism, anti-inflammatory, oxidative stress, and damage mechanisms will likely become a hot topic in the future

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