PJB-2024-102
Evaluation of the genotoxicity in Jordanian paint workers' lymphocytes
maysa
Abstract
One of the largest manufacturing industries in the world is the paint. Certain compounds included in paints have been identified as carcinogenic. The aim of this study was to detect the DNA damage in lymphocyte of Jordanian paint workers by using Comet and micronucleus assays. In this research the genotoxic impact of paint molecules was evaluated in blood peripheral lymphocytes of 50 paint workers with healthy control using micronucleus and Comet assays. The paint worker group's chromosomal abnormalities showed a high frequency of MNi to those in the unexposed group. According to OTM and % tail DNA parameters, the exposed group had significantly more DNA damage than the unexposed group (p < 0.001). In conclusion the high frequency of DNA damage Index found in this research emphasizes the critical need for action, to lower the heightened risk of cancer, as well as to impose strict health regulations and use of suitable protective gear at work.
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