PJB-2022-523
PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL ACTIVITY OF ALBIZIA LEBBECK, ZIZIPHUS JUJUBA AND MORINGA OLEIFERA
Sumra Jabeen
Abstract
Antimicrobial resistance has increased morbidity and death as a result of medical treatment delays and rising health-care expenses. The study's goals and objectives were to investigate plants with medicinal importance like Albizia lebbeck, Ziziphus jujuba and Moringa oleifera. Different plant extracts were prepared for quantitative phytochemical analysis and their antimicrobial activity was determined using two different bacterial strains, Staphylococcus aureus and Escherichia coli. The highest value of alkaloids content (11%) was determined in Moringa oleifera, while highest phenolic (26.2 mg GAE/g Dry Extract) and carbohydrate content (12.41 mg/g dry extract) was reported in aqueous and ethanol extract of Ziziphus jujube, respectively. The highest protein content (17.2 mg/g Dry Extract) was found in diethyl ether extract of Albizia lebbeck. Butanol extract (10 mg) of Albizia lebbeck gave maximum zone of inhibition (14.5±0.55 mm) against Staphylococcus aureus while acetone extract of this plant showed maximum zone of inhibition (12.4±0.88 mm) against E. coli. Ethanol extract (10 mg) of Ziziphus jujuba showed maximum zone of inhibition (11.5±0.25 mm) against Staphylococcus aureus while acetone extract of this plant showed maximum zone of inhibition (10.9±0.42 mm) against E. coli. Ethanol extract (10 mg) of Moringa oleifera exhibited maximum zone of inhibition (13.9±0.41 mm) and (14.2±0.61 mm) against Staphylococcus aureus and E. coli, respectively. Ethanolic extracts were more potent than other extracts as they gave more inhibitory efficacy against the bacterial strains tested and showed promise as a novel medication source for treating infections caused by these pathogens.
Keywords: medicinal plants; screening; quantitative; antibacterial
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