PJB-2020-366
Extraction and evaluation of pharmacological activity of pigments from Purple Cam, Vietnam (Peristrophe bivalvis (L.) Merr)
Mai Van Hung
Abstract
Objective: Acquiring pigment extract to evaluate the antioxidant and toxic activity for human lung and liver cancer cell lines. Methods: Take Purple Cam stems and leaves to boil in distilled water; spin the vacuum to obtain a high pigment. This extract tested antioxidant activity, anti-inflammatory activity, and cytotoxic activity of A549 lung and Hep3B liver cancer in humans. Results: extracts from the leaves and purple mulberry leaves with an extraction efficiency of 9.16%, the pigment extract obtained with antioxidant activity at the test concentration of 500µg/ml had a percentage of inhibition (% Inhibition) reached 71.04. Both the test concentrations of 30 µg/ml and 100 µg/ml, the pigment of rosemary, have no anti-inflammatory activity but have the ability to kill human lung cancer cells A549 and Hep3B human liver at levels average. Conclusion: The extract of Purple Cam does not show anti-inflammatory activity but it is capable of killing human lung cancer cell and liver cancer.
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