PJB-2017-839
Screening of Angelica glauca roots for its In vitro chemical composition, phyto-toxic and antibacterial activity
Khaleeq U Zaman
Abstract
In vitro biological activities including phytotoxic, antibacterial activities as well as phytochemical screening of the various fractions from the root of Angelica glauca were investigated. The data revealed that all the extracted frictions showed variable antibacterial activities. Klebsiella pneumonia was the most resistant bacterial strain among the tested strains and Xanthomonas compestris was the most responsive strain. Ethyl acetate, chloroform, methanol and petroleum ether fractions showed inhibitory activities against all the tested strains. Chloroform friction showed highest activity followed by ethyl acetate and butanol and aqueous extracted samples were found least responsive. Butanol and n-hexane extracted samples showed maximum phytotoxic activity followed by ethanol as compared to control and crude methanol and water fractions on the other hand showed lowest phytotoxic activity. Phyto-chemical analysis revealed the presence of proteins, carbohydrates in all the extracts while presence of tannins was not confirmed in any friction. Alkaloids were reported in different frictions exluding n-hexane, water and ethyl acetate. Similarly, saponines were present only in butanol and water extracted samples. Lipids were found in all the extracted samples except methanol, water and petroleum ether extracted samples while sterols were found in all the extracts except butanol and water.
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