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Abstract

The present research work was designed to investigate Acacia ampliceps Maslin for its phytochemical screening and antimicrobial potential. Results showed that major classes of natural product detected were alkaloids, tannins, reducing sugars, saponins, flavonoids, terpenoids and anthraquinones. Furthermore, we examined antibacterial activity of the four different solvent extract samples (Ethyl acetate, ethanol, chloroform and methanol) against a panel of microorganisms (Bacillus subtilis, Xanthomonas, Pseudomonas aeruginosa, Escherichia coli and Citrobacter) by disc-diffusion assay using concentration of 1mg and 2mg/disc. It was found that the maximum zone of inhibition of ethanol extracted sample against Xanthomonas (173 %) to be the best one followed by ethyl acetate extracted sample against Xanthomonas (158 %). likewise lowest zone of inhibition was measured for chloroform extracted sample against all bacterial strains (0 %). Pseudomonas aeruginosa was most resistant but Xanthomonas specie was most susceptible. These results show that aerial parts of Acacia ampliceps Maslin have a potential broad spectrum antibacterial activity. It was concluded that the extracts have potential for isolation of phytochemical and antimicrobial compounds for the pharmaceutical industry. The above results exposed that Acacia amplicepes have tremendous antibacterial activity and can be used for disease treatment.

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