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KINETICS OF IMPROVED CITRIC ACID PRODUCTION BY MUTANT STRAIN OF ASPERGILLUS NIGER.
Abstract
The present investigation deals with the kinetics of improved citric acid production by Aspergillus niger. A laboratory scale stirred fermentor of 9-L working volume was used for cultivation. The mutant strain of Aspergillus niger NO-2 showed enhanced citrate activity (87.60 * 0.3a g/l) over the parental strain GCB-75 (19.53 = 0.2 g/l) and other mutant derivatives (49.85 k 0.2a g/l citric acid in case of mutant UV-5 &. 76.82 # 0.6b g/l in case of mutant NG-7). The specific productivity of NG-2 (qp - 0.057 ; 0.05a g/g cells/h) was several folds higher than other strains. All other kinetic parameters includil yield coefficients and volumetric rates also revealed the hyperproducibility of citric acid by using mutant NG-2 as the organism of choice
