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Mutation of a locuscotrolling heterocaryon compatibility in nuerospora crassa
Abstract
DURING THE ISOLATION OF TRYTOphan auxo trophs by irradiating the conidia of emenon a astrain of neurospora crassa , a mutant, A336a. was isolated which was heterocaryon negative with represntatives of both the joci tryptophan-l and tryptophan-2. Genetical investigation have revealed that A336a is a tryp-2 mutant which is heterocaryonnegative with tryp-l mutants bebecause a locus controlling heterocaryon formation has mutated in it. The locus in which has mutated allows heterocaryons formation with strains carrying the mutated allele but inhibits heterocaryon formation with strains carrying the trypeallels. Strains having the same mating type allele formed vigorously growing heterocaryons while strains having the opposite mating-type

