Paper Details

PJB-2009-352

EVALUATION OF NEMATOCIDAL ACTIVITY IN NATURAL HONEY

M. KAMRAN AZIM* AND M. SAJID
Abstract


Nematode parasites cause serious diseases in humans and livestock animals. The present study was undertaken to explore the effect of honey on the model nematode Caenorhabditis elegans. In vitro immersion tests showed that honey samples exhibited strong paralyzing effects on different developmental stages of C. elegans with LD90 in the range of 0.75-1.5%. Among the honey tested, Plactranthus honey showed most potent activity with LD90 of 0.75% followed by Acacia honey (LD90 0.75-1.5%). This study pointed out the potential of honey as an antinematodal agent.

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