PJB-2025-342
Characterization of Cyanobacteria from Fresh Water for Potential Antimicrobial Activity
Sundus Nisar
Abstract
Multidrug resistance (MDR) bacterial infections are a growing global health concern. As a result, there is a growing need to discover effective antimicrobial agents from non-conventional sources. In recent years, Cyanobacteria have received significant attention in basic research due to their ability to produce various antimicrobial compounds making them a promising source of novel therapeutics against MDR strains. Objectives: To isolate and characterize of Cyanobacterial strains from fresh water streams of Haripur city for their potential antimicrobial activity. Methods: A total of ten water samples were collected from which thirteen cyanobacterial strains were isolated and tested for antimicrobial activity against four pathogens including Pseudomonas aeruginosa, Bacillus, Staphylococcus aureus and Escherichia coli. Results: Nine strains exhibited antimicrobial activity against all tested pathogens. Morphological and biochemical analysis showed that 50% of the isolated strains resembled Nostoc muscorum, 30% with Oscillatoria and 20% were similar with Microcystis species. Conclusions: These findings suggest that cyanobacteria from freshwater sources possess bioactive compounds with potential application in the pharmaceutical industry for the development of new antibiotics.
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