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Phytochemical screening and evaluation of antibacterial and antifungal activities of Jasminum sambac (L.) Aiton cultivated in Iraq
Abstract
Jasminum sambac (L.) Aiton (sambac jasmine) of the Oleaceae family is an evergreen perennial plant. It has been used medicinally for a very long time. Traditional medicine has long made use of the several phytochemicals found in Arabian jasmine. The antibacterial and chemical composition of Iraqi-grown Jasminum sambac leaves investigated. Alkaloids, terpenoids, flavonoids, and 70% ethanolic extract were used. The GC-MS analysis of the hexane extract revealed many bioactive components, such as vitamin E, stigmasterol, oleic acid, gamma-tocopherol, and alpha-tocopheryl acetate. In order to determine the efficacy against different types of bacteria and fungi antimicrobial experiments were conducted. Tests for antimicrobial action revealed that it effectively suppressed the growth of Candida albicans fungus, Gram-positive Staphylococcus aureus bacteria, and Staphylococcus epidermidis, but had no effect against Klebsiella sp. and Gram-negative Escherichia coli. Antimicrobial and antifungal efficacy varied with concentration. The results suggested that secondary metabolites of Jasminum sambac showed pharmaceutical-grade antibacterial activity. The development of new antimicrobial drugs requires more research for the identification of specific chemicals and the processes by which they work
