PJB-2025-299
PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF JASMINUM SAMBAC CULTIVATED IN IRAQ
Nawras Khairi Fadhil
Abstract
Jasminum sambac (L.) Aiton, often known as Arabian jasmine, is a plant with a diverse phytochemical profile that has long been employed in ethnomedicine for its therapeutic benefits. This study looks at the chemical composition and antibacterial activity of J. sambac leaves grown in Iraq. The 70% ethanolic extract contained alkaloids, terpenoids, and flavonoids, but no saponins. GC-MS analysis of the hexane extract provide various bioactive chemicals, including alpha-tocopheryl acetate, gamma-tocopherol, oleic acid, stigmasterol, and vitamin E, which have antimicrobial, antioxidant, and anti-inflammatory properties. Antimicrobial assays revealed concentration-dependent antibacterial and antifungal activity, with significant inhibition of Gram-positive bacteria (Staphylococcus aureus, Staphylococcus epidermidis) and the fungus Candida albicans, but little activity against Gram-negative bacteria (Escherichia coli, Klebsiella sp.). These findings confirm J. sambac's potential as a natural source of antibacterial drugs, with a variety of secondary metabolites contributing to its therapeutic efficacy. To create innovative antimicrobial medicines, more research into the isolation of specific chemicals and the processes underlying their action is required.
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