PJB-2025-250
ANTIFUNGAL ACTIVITY OF SOME SPECIES OF FAMILY POACEAE
Tahira Naz
Abstract
Objective: The evolution of antifungal medications that are less hazardous and more effective is necessary to treat aspergillosis. The objective of the current investigation was to determine the antifungal property of various fractions of the root and aerial parts of the species Elymus semicostatus ,Cymbopogon jwarancusa, Dichanthium annulutum, Saccharum spontaneum and Saccharum munja of family Poaceae.
Methods: Plants and their extracts are used as medication against communicable diseases. In this study, Elymus semicostatus, Cymbopogon jwarancusa, Dichanthium annulutum, Saccharum spontaneum and Saccharum munja aerial parts and roots were extracted with methanol, n-hexane, ethyl acetate and chloroform in order to study their antifungal properties in vitro.
Results: The aerial part of methanolic extract of Elymus smicostatus inhibited growth of Aspergillus flavus 70% and the root part of methanolic extract showed 65% at concentration of 24µg/mL. The aerial part of chloroform extract of Cymbopogon jwarancusa inhibited growth of Aspergillus flavus 70% and the root part of chloroform extract showed 60%. The aerial part of chloroform extract of Cymbopogon jwarancusa inhibited growth of Aspergillus niger 57% and the root part of chloroform extract showed 50% activity.
Conclusion:
Keeping in view the antifungal effect of various fraction may lead very potent antifungal pure natural product by further isolation and purification from the most effective fractions.
Keywords: Elymus semicostatus, Cymbopogon jwarancusa, Dichanthium annulutum, Saccharum spontaneum and Saccharum munja Antifungal activity, n-hexane, Ethyl acetate, Chloroform
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