Paper Details

PJB-2025-246

Genotoxic Assessment of Occupational Exposure to Pesticides in Strawberry Field Workers

 

Muhammad Muddassir Ali
Abstract

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Pesticides are the chemically defined substances that are generally applied in fields to combat, prevent or control pests that affect the crop’s yield and quality. Irrational application of pesticides results in collateral effects and can harm the immune system, respiratory system, nervous system, endocrine system and reproductive organs. In this study, comet and micronucleus assays were conducted to evaluate the genotoxic effects of pesticides in strawberry field workers. Forty mouthwash samples were used and divided into two groups: the study group (occupationally exposed to pesticides in strawberry fields) and the control group (which has no history of pesticide exposure). A statistically significant increase in micronucleated cells was noted in exposed (196.6 ± 26.47) group compared to the control group (36.25 ± 5.05). Moreover, the exposed groups also had a substantial increase in DNA damage (130.35±12.20) as compared to the control group (42.5±0.707). These result reveal potential health risks of continued insecticide exposure and emphasize the need of regular biomonitoring, protective practices and strict pesticide regulation to safeguard agriculture workers.

 

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