PJB-2024-329
INVESTIGATION OF THE IMPACT OF OF [1-(2-ETHYL, 6-HEPTYL) PHENOL] ON MORPHOLOGICAL FEATURES AND ULTRA-STRUCTURES OF ASPERGILLUS FUMIGATUS AND CANDIDA ALBICANS
Amal A.I. Mehkawy
Abstract
Antimicrobial medications can be found in abundance in naturally occurring substances. Microbial resistance is the primary cause of the current global difficulty in accelerating the discovery of new antimicrobial medications. 1-(2-Ethyl, 6-Heptyl) Phenol (EHP) is a naturally occurring substances compound that was previously obtained by benzene from Cuminum cyminum (C. cyminum, cumin) Egyptian seeds. It demonstrated great action towards a number of pathogenic microorganisms. The study was done on how EHP affected the morphological characteristics and ultra-structures of Candida albicans (C. albicans) and Aspergillus fumigatus (A. fumigatus). Major modifications of morphological features and altered of ultrastructure of tested microbial isolates were observed. Thus, this article describes the morphological and ultrastructure reductions in cellular structures that indicate the role of the evaluated natural product's antimicrobial efficacy which derived from Cuminum cyminum which cultivated in various regions.
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