PJB-2024-174
Promising efficacy of myrrh gum resin components to control candidiasis growth
Amira Hassan Alabdalall
Abstract
Medicinal plants have a long and significant history of being used for their healing properties. One famous example is Commiphora, which is mostly found in the southern part of Arabia. The objective of this research was to evaluate the effectiveness of a water-based extract obtained from two different varieties of myrrh in suppressing the proliferation of Candida spp. at different concentrations. The inhibitory activity of the aqueous extract of two different varieties of myrrh, commonly used in traditional medicine, was assessed against five pathogenic yeasts using the diffusion technique. The strains involved in the study were Candida albicans (ATCC 14053), Candida neoformans (ATCC 66031), Candida laurentii (ATCC 18803), Candida guilliermondii (ATCC 6260), and Candida tropicalis (ATCC 66029). Mass spectrum was used to analyze myrrha's chemical composition for antimicrobial chemicals. The results showed that the aqueous extract of both tested species of Myrrha (Commiphora myrrha and Commiphora molmol) shown inhibitory effects on all tested isolates. Moreover, it was discovered that the inhibitory impact decreased with increasing concentrations of Myrrha. During the chemical examination of the Myrrha, it was noted that the material included 12 components known for their antimicrobial properties. The components described before are as follows: The specified chemical compounds consist of β-Elemene, β-bisabolene, Dihydro butyl bezodoxepin, Tetradecanol, methyl palmitate, Tribenzo-1,2,3,4,5,6 anthracene, 9-Eicosene, 2-bromo-4-fluoro-N-(thiophen-2-ylmethyl) aniline, Octadecenoic acid methyl ester, dehydroabietic acid, and Docosene.
The essential oil derived from two varieties of myrrha shown the most significant effects on Candida tropicalis (ATCC 66029), Candida guilliermondii (ATCC 6260), Candida laurentii (ATCC 18803), Candida neoformans (ATCC 66031), and Candida albicans (ATCC 14053). An analysis of the myrrha's chemical composition revealed that it was shown that it consists of 19 known components, of which 12 compounds have been proven by research to suppress the growth of microorganisms.
To Cite this article:
Download
