Back to Contents

Pak. J. Bot., 47(SI): 139-146, 2015.

FREE FULL TEXT PDF

COMPARATIVE ANALYSIS OF THE BIOLOGICAL ACTIVITIES OF BIO-INSPIRED GOLD NANO-PARTICLES OF PHYLLANTUS EMBLICA FRUIT AND BETA VULGARIS BAGASSE WITH THEIR CRUDE EXTRACTS

BASHIR AHMAD^1*, NABIA HAFEEZ¹, SHUMAILA BASHIR², MIDRARULLAH¹,

SADIQ AZAM¹, IBRAR KHAN¹ AND SAHAR NIGAR¹

¹Centre for Biotechnology & Microbiology, University of Peshawar, Pakistan

²Department of Pharmacy, University of Peshawar, Pakistan

^*Corresponding author’s e-mail: bashirdr2001@yahoo.com

Abstract: Over the last few decades, the appearance of the resistant strains as a result of the increased exploitation of antibiotics has challenged the researchers to develop improved techniques. One such technique makes use of the green approach for synthesizing metallic nano-particles. The characteristic, small size and the large surface area to volume ratio of these nano-particles mark their potential to fight against these pathogens. Two types of gold nano-particles (AuNPs) were synthesized using the aqueous extract of Phyllanthus emblica fruit and Beta vulgaris bagasse with tetra-chloroauric acid (HAuCl₄.3H₂O) as a metal precursor. Biogenic AuNPs so synthesized were investigated for their antimicrobial potential in relation to activities of the aforementioned plant materials in crude methanolic, ethanolic, acetone and aqueous extracts. The antioxidant and haemagglutination activities were also studied.

Keywords: Antibacterial, antifungal, anti-oxidant, haemagglutination, Phyllanthus emblica, Beta vulgaris.