Google
 

Back to Contents

 

Pak. J. Bot., 46(1): 363-368, 2014.

FREE FULL TEXT PDF

  Back to Contents
   

 

  Updated: 15-01-14

 

 

IN VITRO ANTIBACTERIAL ACTIVITY OF METHANOL AND WATER EXTRACTS OF ADIANTUM CAPILLUS VENERIS AND TAGETES PATULA AGAINST MULTIDRUG RESISTANT BACTERIAL STRAINS

 

MUHAMMAD MEDRAR HUSSAIN1*, BASHIR AHMAD1, ELISA RASHID1, SAIMA HASHIM2, KHAN BAHADAR MARWAT3, ASAD JAN4

 

Abstract: The aim of present study was to screen the antimicrobial activities of extracts of leaves and stems of Adiantum capillus veneris and Tagetes patula against multidrug-resistant (MDR) bacterial strains. Extracts from the leaves and stems of these plants were extracted with methanol and water and tested for their antibacterial activity by disc diffusion method against ten MDR bacterial strains i.e., Citrobacter freundii, Escherichia coli, Providencia, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, Proteus vulgaris, Salmonella typhi, Shigella and Vibrio cholerae. Leaves methanol extract (LME) of Adiantum showed maximum Zone of Inhibition (ZI) against Providencia, Klebsiella pneumoniae, Shigella, Vibrio cholerae, Staphylococcus aureus, Proteus vulgaris and Salmonella typhi, whereas its stem methanol extract (SME) was very active against Escherichia coli, Klebsiella pneumoniae and Salmonella typhi. Similarly LME of Tagetes showed highest ZI against Escherichia coli and Vibrio cholerae while SME showed highest ZI to Escherichia coli, Vibrio cholerae, Providencia, Shigella and Klebsiella pneumoniae. Leaves water extract (LWE) of Adiantum was very active against all ten bacterial strains while its stem water extract (SWE) showed maximum ZI against Escherichia coli, Klebsiella pneumoniae and Salmonella typhi, Shigella, Proteus vulgaris and Providencia. LWE of Tagetes was only active against Vibrio cholerae whereas SWE was very active against Salmonella typhi and active against P. vulgaris, Citrobacter freundii and Vibrio cholerae. It was concluded from this study that extracts of both Adiantum and Tagetes have prominent activities against most of the MDR bacterial strains and needs further studies for utmost benefits.

 


1Department of Microbiology, Abasyn University Peshawar, Peshawar, Pakistan

2Department of Weed Science, The University of Agriculture Peshawar, Pakistan

3SBBU, Sheringal, Upper Dir, Pakistan

4Institute of Biotechnology & Genetic Engineering, The University of Agriculture Peshawar, Pakistan

*Corresponding author e-mail: medrarbiotech@gmail.com


   
   

 

   
Back to Contents  

 

  Back to Contents