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Pak. J. Bot., 44(1): 389-391, 2012. |
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Updated: 03-02-12 |
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ANTI-EMETIC ACTIVITY OF SOME LEGUMINOUS PLANTS
MUHAMMAD MOHTASHEEM UL HASAN*, IQBAL AZHAR, S. MUZAMMIL, SALMAN AHMED AND SYED WASEEMUDDIN AHMED
Abstract: Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity.
Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan. |
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